Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968951 | 0.82 | HSD17B1 (0.45) | OPRM1ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7171832 | 0.81 | ALDH1A1 (0.43) | OPRM1OPRK1ALDH1A1HSD17B10GAA | |
| SCHEMBL14038361 | 0.78 | ESR2 (0.41) | ESR1ESR2TTRALDH1A1HSD17B10 | |
| SCHEMBL9968854 | 0.77 | MIF (0.37) | ESR1ESR2TTRGAAMIF | |
| SCHEMBL21495176 | 0.77 | ALDH1A1 (0.38) | ESR1ESR2ALDH1A1HSD17B10GAA | |
| SCHEMBL28582810 | 0.77 | DRD2 (0.39) | OPRM1OPRK1ESR1ESR2TTR | |
| SCHEMBL3408615 | 0.77 | ESR1 (0.45) | OPRM1OPRK1ESR1ESR2ALDH1A1 | |
| SCHEMBL2935731 | 0.76 | DRD2 (0.41) | OPRM1OPRK1ALDH1A1HSD17B10GAA | |
| SCHEMBL28027452 | 0.75 | DRD2 (0.49) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10918502 | 0.75 | DRD2 (0.49) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| EP-2651886-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| CN-103282348-A | Method for depigmenting keratin materials using resorcinol derivatives | OREAL | 2013-09-04 | — | — | CN | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | KRT18, KLHL20, IK | OPRM1 4756/4885OPRK1 2772/4885ESR1 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.