Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054219 | 0.84 | KEAP1 (0.46) | KEAP1NFE2L2KMT2AGAAMEN1 | |
| SCHEMBL27541104 | 0.82 | METAP2 (0.56) | KMT2AALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18322811 | 0.81 | ALDH1A1 (0.44) | KEAP1NFE2L2KMT2AGAAMEN1 | |
| SCHEMBL3100559 | 0.81 | KEAP1 (0.51) | KEAP1NFE2L2KMT2AGAAMEN1 | |
| SCHEMBL8881578 | 0.81 | KMT2A (0.54) | KEAP1NFE2L2KMT2AGAAMEN1 | |
| SCHEMBL6608554 | 0.76 | ALDH1A1 (0.41) | KEAP1NFE2L2KMT2AALDH1A1LMNA | |
| SCHEMBL3263766 | 0.75 | METAP2 (0.76) | KEAP1NFE2L2KMT2AGAAMEN1 | |
| SCHEMBL6937180 | 0.74 | KMT2A (0.55) | KEAP1NFE2L2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4126086 | 0.74 | MEN1 (0.60) | KMT2AGAAMEN1ALDH1A1LMNA | |
| SCHEMBL18179825 | 0.74 | MEN1 (0.60) | KMT2AGAAMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462520-A | Preparation method of substituted benzoate derivative | 上海皓元医药股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119462520-A | Preparation method of substituted benzoate derivative | 上海皓元医药股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2012079583-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS | AARHUS UNIVERSITET (DK) | 2012-06-21 | — | — | WO | disclosed |
| EP-0270201-A1 | A method for the preparation of a 2,4-diamino-3-oxy-pyrimidine derivative | ORION-YHTYMÀ OY (FI) | 1988-06-08 | — | — | EP | disclosed |
| US-4620002-A | 2-pyrimidyl alkanesulfonates | EASTMAN KODAK COMPANY (US) | 1986-10-28 | — | — | US | disclosed |