SCHEMBL9937753

SCHEMBL9937753

[O]c1cccc(-c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
ALDH1A1 P00352 3/20 0.47
HDAC8 Q9BY41 2/20 0.46
KMO O15229 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
ALOX5 P09917 1/20 0.46
ACMSD Q8TDX5 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 2/20 0.45
ATM Q13315 2/20 0.45
APAF1 O14727 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
XBP1 P17861 1/20 0.45
PTBP1 P26599 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277850 0.97 ALDH1A1 (0.50) MAOAALDH1A1HDAC8KMOHDAC4
SCHEMBL9937109 0.95 KMO (0.52) MAOAALDH1A1HDAC8KMOHDAC4
SCHEMBL11898508 0.92 HSD17B1 (0.43) MAOAALDH1A1HDAC8KMOHDAC4
SCHEMBL9936836 0.84 KMO (0.52) MAOAALDH1A1HDAC8KMOHDAC4
SCHEMBL29004513 0.83 ALDH1A1 (0.54) ALDH1A1HDAC2MEN1KMT2ANPC1
SCHEMBL28852357 0.83 ESR1 (0.70) ALOX5MEN1KMT2ACYP3A4CYP2C9
SCHEMBL4895260 0.83 ALDH1A1 (0.50) MAOAALDH1A1HDAC8KMOHDAC4
SCHEMBL31254135 0.80 ALDH1A1 (0.64) MAOAALDH1A1KMOALOX5ACMSD
SCHEMBL22113250 0.80 ALDH1A1 (0.64) MAOAALDH1A1KMOALOX5ACMSD
SCHEMBL29792069 0.80 ALDH1A1 (0.64) MAOAALDH1A1KMOALOX5ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2675800-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF Institute Of Chemistry, Chinese Academy Of Sciences (CN) 2013-12-25 EP disclosed
US-20130331583-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF Institute of Chemistry, Chinesse Academy of Sciences 2013-12-12 US disclosed
WO-2012079545-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF CHINESE ACADEMY OF SCIENCE INSTITUTE OF CHEMISTRY (CN) 2012-06-21 WO disclosed