SCHEMBL4895260

SCHEMBL4895260

[O]c1cc2cccccc-2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
MAOA P21397 1/20 0.43
MAPT P10636 3/20 0.43
HTT P42858 3/20 0.43
LMNA P02545 2/20 0.43
HDAC8 Q9BY41 2/20 0.42
KMO O15229 1/20 0.42
NOTUM Q6P988 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
ALOX5 P09917 1/20 0.42
BACE1 P56817 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ATM Q13315 2/20 0.41
ASIC3 Q9UHC3 1/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2841422 0.88 ALDH1A1 (0.53) ALDH1A1MAOAMAPTHTTLMNA
SCHEMBL277850 0.85 ALDH1A1 (0.50) ALDH1A1MAOAMAPTHTTLMNA
SCHEMBL9937753 0.83 MAOA (0.48) ALDH1A1MAOAMAPTHTTLMNA
SCHEMBL9937109 0.83 KMO (0.52) ALDH1A1MAOAHTTHDAC8KMO
SCHEMBL11898508 0.78 HSD17B1 (0.43) ALDH1A1MAOAHTTHDAC8KMO
SCHEMBL9936836 0.77 KMO (0.52) ALDH1A1MAOAMAPTHTTLMNA
Biphenyl SCHEMBL641103 0.74 ALDH1A1 (0.75) ALDH1A1MAOAMAPTHTTLMNA
SCHEMBL5873579 0.74 ALDH1A1 (0.61) ALDH1A1MAOAMAPTHTTLMNA
Biphenyl SCHEMBL5068276 0.73 ALDH1A1 (0.90) ALDH1A1MAOANOTUMALOX5BACE1
SCHEMBL31274555 0.73 ALDH1A1 (0.50) ALDH1A1MAOAMAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221750-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-18 US claimed
US-20190185457-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2019-06-20 US claimed
US-11997917-B2 Quantum dot electroluminescence device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-28 US disclosed
EP-3674290-B1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2024-05-22 EP disclosed
US-20240114765-A1 QUANTUM DOT ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-04-04 US disclosed
US-11925106-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-03-05 US disclosed
US-20240027927-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-01-25 US disclosed
EP-4310593-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM Business Innovation Corp. (JP) 2024-01-24 EP disclosed
CN-117434803-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2024-01-23 CN disclosed
US-20240012343-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-01-11 US disclosed
EP-4303660-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM Business Innovation Corp. (JP) 2024-01-10 EP disclosed
EP-2492988-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sumitomo Chemical Company, Limited (JP) 2012-08-29 EP disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20120199825-A1 ORGANIC ELECTROLUMINESCENT DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-09 US disclosed
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1816152-A1 POLYMERIZABLE COMPOSITION TOYO INK MFG. CO., LTD. (JP) 2007-08-08 EP disclosed
US-7244861-B2 Benzene compound and salt thereof EISAI CO., LTD. (JP) 2007-07-17 US disclosed
US-20040138271-A1 Benzene compound and salt thereof EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-07-15 US disclosed
EP-1375472-A1 BENZENE COMPOUND AND SALT THEREOF Eisai Co., Ltd. (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11925106-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound CCNB1, CCNA1, CCNT1 ALDH1A1 642/4885MAOA 2493/4885MAPT 2220/4885
US-20190185457-A1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND CRY1, NAP1L1, CYP1A1 ALDH1A1 27/4885MAOA 113/4885MAPT 2333/4885
US-20040138271-A1 Benzene compound and salt thereof INSR, SLC5A1, IRS1 ALDH1A1 1736/4885MAOA 3749/4885MAPT 4358/4885
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 ALDH1A1 1369/4885MAOA 1292/4885MAPT 1563/4885
US-20190221750-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND CRY1, CRY2, MCM4 ALDH1A1 742/4885MAOA 2893/4885MAPT 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.