Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991571 | 0.85 | CASP1 (0.49) | CASP1CA12CA1CA2CA9 | |
| SCHEMBL992013 | 0.83 | CASP1 (0.50) | CASP1IDO1ALDH1A1 | |
| SCHEMBL3419896 | 0.81 | CASP1 (0.50) | CASP1ALDH1A1 | |
| SCHEMBL13533564 | 0.80 | CASP1 (0.52) | CASP1ALDH1A1 | |
| SCHEMBL13978206 | 0.80 | TPSAB1 (0.55) | CASP1ALDH1A1 | |
| SCHEMBL991422 | 0.80 | CASP1 (0.55) | CASP1ALDH1A1 | |
| SCHEMBL992370 | 0.79 | CASP1 (0.53) | CASP1ALDH1A1 | |
| SCHEMBL991807 | 0.79 | CASP1 (0.53) | CASP1ALDH1A1 | |
| SCHEMBL993781 | 0.77 | CASP1 (0.52) | CASP1ALDH1A1 | |
| SCHEMBL13977813 | 0.77 | CASP1 (0.52) | CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451776-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-09-18 | — | — | EP | disclosed |
| US-9732047-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2240206-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170029386-A9 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-9393329-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160185737-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-06-30 | — | — | US | disclosed |
| US-9266846-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-9266846-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150094465-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| US-20150078997-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8877157-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-8852553-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130315822-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| US-8361438-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120328514-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2451776-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005322-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2240206-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20090252676-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009089022-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094465-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20170029386-A9 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20130315822-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20160185737-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20120328514-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20150078997-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
| US-20090252676-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885IDO1 813/4885CA12 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.