Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990816 | 0.87 | ALOX5 (0.36) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL7290584 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL10698801 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL11569174 | 0.84 | SLC6A2 (0.33) | ALDH1A1TSHRHRH3ALOX5SLC6A2 | |
| SCHEMBL11245023 | 0.82 | TUBB4A (0.32) | ALOX5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10958091 | 0.77 | CHRM2 (0.35) | ALDH1A1KDM4EMAPTTHRBTDP1 | |
| SCHEMBL14313506 | 0.76 | SLC6A2 (0.34) | ALDH1A1TSHRHRH3ALOX5SLC6A2 | |
| SCHEMBL11001585 | 0.75 | PRMT6 (0.53) | CYP2C19CYP1A2SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL13990460 | 0.72 | ALDH1A1 (0.40) | ALDH1A1GAATSHRHRH3CYP2C19 | |
| SCHEMBL11255888 | 0.72 | GSR (0.40) | ALDH1A1TSHRHRH3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651910-B1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-2752408-B1 | Preparation of aminomethyl furans and alkoxymethyl furan derivatives from carbohydrates | ARCHER DANIELS MIDLAND CO (US) | 2016-05-18 | — | — | EP | disclosed |
| US-8901326-B2 | Preparation of aminomethyl furans and alkoxymethyl furan derivatives from carbohydrates | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2752408-A1 | Preparation of aminomethyl furans and alkoxymethyl furan derivatives from carbohydrates | Archer-Daniels-Midland Company (US) | 2014-07-09 | — | — | EP | disclosed |
| US-20140148605-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-05-29 | — | — | US | disclosed |
| US-8669383-B2 | Preparation of aminomethyl furans and alkoxymethyl furan derivatives from carbohydrates | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-03-11 | — | — | US | disclosed |
| US-20130303791-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2651910-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | Archer-Daniels-Midland Company (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082665-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148605-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | DERA, HRH3, HRH4 | ALDH1A1 395/4885KDM4E 1509/4885MEN1 1052/4885 |
| US-20130303791-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | DERA, HRH3, HRH4 | ALDH1A1 395/4885KDM4E 1509/4885MEN1 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.