Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668760 | 0.83 | GAA (0.55) | HPGDLMNAGAAL3MBTL1NPC1 | |
| SCHEMBL374696 | 0.81 | FOLH1 (0.61) | HPGDLMNAGAAL3MBTL1TP53 | |
| SCHEMBL49956 | 0.81 | TSHR (0.50) | HPGDLMNANPC1TP53RAB9A | |
| SCHEMBL8768476 | 0.79 | FOLH1 (0.59) | HPGDLMNAGAAL3MBTL1TP53 | |
| SCHEMBL873231 | 0.79 | HPGD (0.52) | HPGDLMNAGAAL3MBTL1NPC1 | |
| SCHEMBL6043201 | 0.79 | FOLH1 (0.59) | HPGDLMNAGAAL3MBTL1TP53 | |
| SCHEMBL3135001 | 0.79 | LMNA (0.52) | HPGDLMNAGAAL3MBTL1NPC1 | |
| SCHEMBL12765935 | 0.79 | HPGD (0.52) | HPGDLMNAGAAL3MBTL1NPC1 | |
| SCHEMBL619877 | 0.79 | ALDH1A1 (0.52) | HPGDLMNAGAAL3MBTL1NPC1 | |
| SCHEMBL11754063 | 0.79 | HPGD (0.52) | HPGDLMNAGAAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652141-A1 | MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1.4- CYCLOHEXANEDIMETHANOL | Genomatica, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082978-A1 | MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1.4- CYCLOHEXANEDIMETHANOL | GENOMATICA, INC. (US) | 2012-06-21 | — | — | WO | disclosed |