SCHEMBL49956

SCHEMBL49956

CCc1ccccc1C([O])=O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
CLCN2 P51788 1/20 0.46
ALDH1A1 P00352 4/20 0.43
LMNA P02545 1/20 0.43
F2R P25116 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.41
FOLH1 Q04609 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALOX15 P16050 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5690419 0.85 ALDH1A1 (0.47) TSHRALDH1A1LMNAHSD17B10TP53
SCHEMBL2935940 0.83 GABRA1 (0.48) TSHRGABRA1GABRB2CLCN2ALDH1A1
SCHEMBL2171647 0.81 TSHR (0.46) TSHRALDH1A1LMNATP53HTT
SCHEMBL9938909 0.81 HPGD (0.53) TSHRALDH1A1LMNATP53FOLH1
SCHEMBL254888 0.81 HSD17B1 (0.48) TSHRGABRA1GABRB2CLCN2ALDH1A1
SCHEMBL28115 0.81 FOLH1 (0.61) TSHRCLCN2ALDH1A1TP53HTT
SCHEMBL2491928 0.80 GABRA1 (0.50) TSHRGABRA1GABRB2CLCN2ALDH1A1
SCHEMBL7404989 0.80 BCHE (0.43) TSHRALDH1A1LMNAHSD17B10HTT
SCHEMBL8059017 0.80 LIPG (0.53) TSHRALDH1A1LMNATP53HTT
Bicarbonate SCHEMBL14635340 0.79 GABRA1 (0.55) TSHRGABRA1GABRB2CLCN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4291047-A Combating fungi with α-azolyl-β-hydroxy-ketones BAYER AKTIENGESELLSCHAFT (DE) 1981-09-22 US claimed
CN-117957265-A Process for producing dihydroxy compound and process for producing regenerated resin 三菱瓦斯化学株式会社 2024-04-30 CN disclosed
CN-117916325-A Thermoplastic resin composition, molded article, method for producing thermoplastic resin composition, and method for improving transmittance 三菱瓦斯化学株式会社 2024-04-19 CN disclosed
US-20230295373-A1 THERMOPLASTIC RESIN COMPOSITION FOR OPTICAL MATERIAL, MOLDED ARTICLE, COMPOUNDING AGENT, METHOD FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, AND METHOD FOR IMPROVING TRANSMISSIVITY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-21 US disclosed
EP-4198092-A1 THERMOPLASTIC RESIN COMPOSITION FOR OPTICAL MATERIAL, MOLDED ARTICLE, COMPOUNDING AGENT, METHOD FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, AND METHOD FOR IMPROVING TRANSMISSIVITY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-21 EP disclosed
CN-116096779-A Thermoplastic resin composition for optical material, molded article, compounding agent, method for producing thermoplastic resin composition, and method for improving transmittance 三菱瓦斯化学株式会社 2023-05-09 CN disclosed
WO-2023068290-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING AND METHOD FOR IMPROVING TRANSMITTANCE OF THERMOPLASTIC RESIN COMPOSITION 三菱瓦斯化学株式会社 2023-04-27 WO disclosed
CN-115335443-A Method for producing regenerated resin 三菱瓦斯化学株式会社 2022-11-11 CN disclosed
US-8906279-B2 Manufacturing method of polarizing plate protective film, polarizing plate protective film, polarizing plate, and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2014-12-09 US disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
US-5428162-A For protecting organic materials against thermal, oxidative or light-induced degradation CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0644190-A1 Benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1995-03-22 EP disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
US-5367008-A 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers CIBA-GEIGY CORPORATION (US) 1994-11-22 US disclosed
US-5356966-A Stabilizing organic material against oxidative, thermal or light iinduced degradation CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed
EP-0589839-A1 3-(Dihydrobenzofuran-5-yl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-03-30 EP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed