Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621988 | 0.94 | NAMPT (0.40) | NAMPTSNCA | |
| SCHEMBL16621987 | 0.82 | NAMPT (0.42) | NAMPTSMN1; SMN2SNCAHSD11B1L3MBTL1 | |
| SCHEMBL9939770 | 0.80 | RXFP1 (0.38) | TRPV1IDH1 | |
| SCHEMBL9939466 | 0.79 | GRM4 (0.38) | SMN1; SMN2IDH1 | |
| SCHEMBL9938594 | 0.79 | NAMPT (0.41) | NAMPTSMN1; SMN2SNCA | |
| SCHEMBL9939397 | 0.79 | IDH1 (0.40) | TRPV1IDH1 | |
| SCHEMBL9939441 | 0.79 | LMNA (0.42) | SMN1; SMN2 | |
| SCHEMBL9938519 | 0.77 | VNN1 (0.37) | TRPV1IDH1 | |
| SCHEMBL16621983 | 0.77 | IDH1 (0.39) | IDH1 | |
| SCHEMBL9939678 | 0.75 | ROCK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078869-A1 | PYRIDONYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |