Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 1.00 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | BRS3 | P32247 | 10/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938772 | 0.83 | MMP2 (0.71) | MMP2MMP9MMP13DAOBRS3 | |
| Hydrochloric Acid SCHEMBL10695618 | 0.83 | MMP2 (0.70) | MMP2MMP9MMP13DAOBRS3 | |
| SCHEMBL14744177 | 0.80 | MMP2 (0.67) | MMP2MMP9MMP13BRS3GAA | |
| SCHEMBL8653203 | 0.80 | MMP2 (0.67) | MMP2MMP9MMP13BRS3MEN1 | |
| Hydrochloric Acid SCHEMBL14744176 | 0.79 | MMP2 (0.65) | MMP2MMP9MMP13BRS3GAA | |
| SCHEMBL20630812 | 0.79 | MMP2 (0.64) | MMP2MMP9MMP13RNASEH1 | |
| SCHEMBL7424608 | 0.77 | MMP2 (0.61) | MMP2GAA | |
| SCHEMBL5903845 | 0.76 | MMP2 (0.61) | MMP2MMP9MMP13DAOBRS3 | |
| SCHEMBL20630811 | 0.75 | MMP2 (0.60) | MMP2GAA | |
| SCHEMBL4605593 | 0.75 | MMP2 (0.60) | MMP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651413-B1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT (HU) | 2017-11-22 | — | — | EP | disclosed |
| EP-2651413-B1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT (HU) | 2017-11-22 | — | — | EP | disclosed |
| US-9487462-B2 | Inhibitors of matrix metalloproteinases | PHARMAHUNGARY 2000 KFT. (HU) | 2016-11-08 | — | — | US | disclosed |
| US-9487462-B2 | Inhibitors of matrix metalloproteinases | PHARMAHUNGARY 2000 KFT. (HU) | 2016-11-08 | — | — | US | disclosed |
| CN-103347516-B | matrix metalloproteinase inhibitors | Hungary Pharmaceutical 2000 Ltd. (HU) | 2015-10-14 | — | — | CN | disclosed |
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TARGETEX KFT. (HU) | 2013-11-14 | — | — | US | disclosed |
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TARGETEX KFT. (HU) | 2013-11-14 | — | — | US | disclosed |
| EP-2651413-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | Pharmahungary 2000 Kft. (HU) | 2013-10-23 | — | — | EP | disclosed |
| CN-103347516-A | Novel matrix metalloproteinase inhibitors | PHARMAHUNGARY 2000 KFT | 2013-10-09 | — | — | CN | disclosed |
| WO-2012080762-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT. (HU) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080762-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT. (HU) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TIMP3, MMP3, MMP13 | MMP2 6/4885MMP9 5/4885MMP13 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.