Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023085 | 0.92 | MEN1 (0.50) | TRPA1HSD17B1HSD17B2CYP1A2CYP3A4 | |
| SCHEMBL12023092 | 0.90 | PLAU (0.45) | TRPA1HSD17B1HSD17B2CYP1A2CYP3A4 | |
| SCHEMBL4040346 | 0.82 | MEN1 (0.45) | HSD17B1HSD17B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12431423 | 0.81 | ESR1 (0.54) | TRPA1HSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL21153834 | 0.81 | ALDH1A1 (0.50) | TRPA1CYP1A2ESR1ESR2MEN1 | |
| SCHEMBL15274959 | 0.81 | PLAU (0.40) | TRPA1HSD17B1HSD17B2CYP1A2CYP3A4 | |
| SCHEMBL12950047 | 0.80 | TRPA1 (0.50) | TRPA1MEN1KMT2AERN1MAPT | |
| SCHEMBL29742946 | 0.77 | PLAU (0.53) | TRPA1HSD17B1HSD17B2CYP1A2ESR1 | |
| SCHEMBL472325 | 0.77 | PLAU (0.53) | TRPA1HSD17B1HSD17B2CYP1A2ESR1 | |
| SCHEMBL15946479 | 0.75 | TRPA1 (0.52) | TRPA1CYP1A2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277623-A2 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277623-A2 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2011-01-26 | — | — | EP | disclosed |
| EP-1905511-A2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2008-04-02 | — | — | EP | disclosed |
| EP-1905511-A2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2008-04-02 | — | — | EP | disclosed |
| US-6924345-B2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA NORTH AMERICA S.A R.L. (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1448298-A2 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040054105-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2004-03-18 | — | — | US | disclosed |
| US-6660876-B2 | Ethylenically unsaturated, phosphorus-containing, bidentate ligands | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030144440-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2003-07-31 | — | — | US | disclosed |
| WO-2003045552-A2 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |
| EP-0864577-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-6248848-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6143834-A | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0864577-A2 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | Takasago International Corporation (JP) | 1998-09-16 | — | — | EP | disclosed |