Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL20528041 | 0.83 | L3MBTL1 (0.71) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL28737810 | 0.82 | LMNA (1.00) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL29368665 | 0.82 | — | — | |
| 2-Picolinic Acid SCHEMBL674837 | 0.82 | LMNA (1.00) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL7457912 | 0.82 | LMNA (1.00) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL36055 | 0.82 | — | — | |
| 2-Picolinic Acid SCHEMBL149849 | 0.80 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL20721125 | 0.80 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL22835776 | 0.80 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL890376 | 0.80 | LMNA (0.95) | L3MBTL1LMNANAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105779599-B | Kit for detecting metastatic castration resistant prostate cancer drug resistance | 上海美吉生物医药科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| EP-2451966-A1 | METHODS FOR EARLY DETECTION OF BLOOD DISORDERS | UVic Industry Partnerships Inc. (CA) | 2012-05-16 | — | — | EP | disclosed |
| US-20120107859-A1 | METHODS FOR EARLY DETECTION OF BLOOD DISORDERS | UVIC INDUSTRY PARTNERSHIPS INC. (CA) | 2012-05-03 | — | — | US | disclosed |
| WO-2011003182-A1 | METHODS FOR EARLY DETECTION OF BLOOD DISORDERS | UNIVERSITY OF VICTORIA INNOVATION AND DEVELOPMENT CORPORATION (CA) | 2011-01-13 | — | — | WO | disclosed |