Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172544 | 0.87 | APP (0.41) | FAAHCXCL12ACACBMEN1KMT2A | |
| SCHEMBL1818040 | 0.87 | FAAH (0.48) | FAAHACACBMAPK1SMN1; SMN2 | |
| SCHEMBL22122710 | 0.86 | LTA4H (0.50) | FAAHTSHRTP53 | |
| SCHEMBL3924311 | 0.82 | APP (0.46) | ACACBMEN1KMT2AMAPK1 | |
| SCHEMBL8377181 | 0.82 | TSHR (0.55) | FAAHTSHRACACBTP53SMN1; SMN2 | |
| SCHEMBL8376570 | 0.79 | NR5A1 (0.53) | FAAHTSHRACACBTP53SMN1; SMN2 | |
| SCHEMBL20865650 | 0.77 | ACHE (0.45) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9508533 | 0.77 | CYP2D6 (0.54) | FAAHTSHRTP53SMN1; SMN2 | |
| SCHEMBL8519007 | 0.77 | NR5A1 (0.56) | FAAHTSHRMEN1KMT2ATP53 | |
| SCHEMBL4270834 | 0.76 | TSHR (0.64) | FAAHTSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652552-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082299-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |