Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIF18A | Q8NI77 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944873 | 0.90 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1LMNAKIF18AHTR1A | |
| SCHEMBL9947058 | 0.86 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1LMNAKIF18AHTR1A | |
| SCHEMBL9944865 | 0.84 | LMNA (0.49) | ALDH1A1L3MBTL1LMNAHSD17B10GAA | |
| SCHEMBL9944760 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAHSD17B10GAA | |
| SCHEMBL9944868 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL9897859 | 0.82 | KDM4E (0.38) | ALDH1A1KIF18AHSD17B10GAAKDM4E | |
| SCHEMBL9897728 | 0.82 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNAHSD17B10KDM4E | |
| SCHEMBL9944861 | 0.80 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1LMNAHSD17B10GAA | |
| SCHEMBL9944918 | 0.78 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNAHSD17B10GAA | |
| SCHEMBL9944981 | 0.78 | KIF18A (0.45) | ALDH1A1L3MBTL1LMNAKIF18AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | ALDH1A1 126/4885L3MBTL1 3016/4885LMNA 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.