Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL27972307 | 0.91 | TSHR (0.59) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| O-Xylene SCHEMBL11776221 | 0.88 | TSHR (0.56) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| SCHEMBL3833584 | 0.84 | TSHR (0.43) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| SCHEMBL5446748 | 0.82 | KEAP1 (0.56) | TSHRACHEALDH1A1TDP1CA1 | |
| SCHEMBL352788 | 0.82 | ALDH1A1 (0.71) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| SCHEMBL28806536 | 0.82 | TSHR (0.41) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| SCHEMBL995202 | 0.82 | ACHE (0.71) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| O-Xylene SCHEMBL29725142 | 0.81 | TSHR (0.62) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| O-Xylene SCHEMBL27875104 | 0.81 | TSHR (0.62) | TSHRACHEALDH1A1TDP1HSD17B10 | |
| O-Xylene SCHEMBL28085642 | 0.81 | TSHR (0.62) | TSHRACHEALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87107746-A | Insecticidal ethers compound | — | 1988-04-27 | — | — | CN | claimed |
| CN-111187188-A | Synthesis method of substituted thiophenol | 普济生物科技（台州）有限公司 | 2020-05-22 | — | — | CN | disclosed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | disclosed |
| CN-101381333-B | Method for preparing corresponding thiophenol by reduction of aromatic sulfonic acid or derivates thereof | UNIV ZHEJIANG | 2012-09-19 | — | — | CN | disclosed |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | AUCKLAND UNIVSERVICES LIMITED (NZ) | 2012-09-06 | — | — | US | disclosed |
| EP-2456435-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | The Board of Trustees of The Leland Stanford Junior University (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |
| CN-101421272-A | 3-unsubstituted N-(aryl- or heteroarvl)-pyrazolori (1,5-a) pyrimidines as kinase inhibitors | NOVARTIS AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-101381333-A | Method for preparing corresponding phenyl-sulfhydrate by reduction of aromatic sulfonic acid or derivates thereof | UNIV ZHEJIANG (CN) | 2009-03-11 | — | — | CN | disclosed |
| US-20080255150-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2008-10-16 | — | — | US | disclosed |
| US-4382125-A | POLYURETHANE FOAM | BASF WYANDOTTE CORPORATION (US) | 1983-05-03 | — | — | US | disclosed |
| US-4359550-A | USE OF A TRIMERIZATION CATALYST | BASF WYANDOTTE CORPORATION (US) | 1982-11-16 | — | — | US | disclosed |
| US-4359541-A | TRIMERIZATION CATALYSTS | BASF WYANDOTTE CORPORATION (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0056582-A1 | Process for the preparation of polyisocyanurate dispersions modified with halogenated alcohols and compositions prepared therefrom | BASF WYANDOTTE CORPORATION (US) | 1982-07-28 | — | — | EP | disclosed |
| EP-0056583-A1 | Polyisocyanurate polymer dispersions, and cellular and non-cellular polyurethane products prepared therefrom | BASF Corporation (US) | 1982-07-28 | — | — | EP | disclosed |
| EP-0056581-A1 | Process for the preparation of polyisocyanurate dispersions and compositions prepared therefrom | BASF WYANDOTTE CORPORATION (US) | 1982-07-28 | — | — | EP | disclosed |
| US-4326043-A | FIREPROOFING | BASF WYANDOTTE CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4304838-A | FILMS FOR PEELABLE DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4157261-A | PHOTOINITIATOR, CHLORINATED POLYOLEFIN BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1979-06-05 | — | — | US | disclosed |
| US-4050936-A | Image forming process with photopolymer layers between a support and a substrate | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255150-A1 | Novel Compounds | CFTR, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP11B2 | TSHR 2461/4885ACHE 3753/4885ALDH1A1 239/4885 |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | BRDT, NISCH, PAICS | TSHR 3930/4885ACHE 141/4885ALDH1A1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.