SCHEMBL9945690

SCHEMBL9945690

C=CC(=O)OCCCOCCCOCCCOC(=O)C=C

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.74
ALDH1A1 P00352 5/20 0.74
TP53 P04637 3/20 0.74
HIF1A Q16665 3/20 0.74
CYP3A4 P08684 2/20 0.74
HSD17B10 Q99714 1/20 0.74
HPGD P15428 1/20 0.65
THRB P10828 3/20 0.48
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 4/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9945692 1.00 TSHR (0.74) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2921943 1.00 TSHR (0.74) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL26002003 0.98 TSHR (0.78) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL26002001 0.98 TSHR (0.78) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL24404688 0.96 TSHR (0.83) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9945691 0.96 TSHR (0.83) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12761985 0.95 TSHR (0.82) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL14129252 0.95 TSHR (0.82) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17449872 0.95 TSHR (0.82) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL321925 0.93 TSHR (0.85) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878946-B Tire tread rubber for new energy heavy truck, and preparation method and application thereof 山东华盛橡胶有限公司 2025-04-15 CN disclosed
CN-118852750-B High-wear-resistance low-noise tire tread rubber for electric buses and preparation method and application thereof 山东华盛橡胶有限公司 2025-04-01 CN disclosed
CN-118995186-B Slick water fracturing fluid and preparation process and fracturing process thereof 德仕(成都)石油科技有限公司 2025-02-11 CN disclosed
CN-118995186-A Slick water fracturing fluid and preparation process and fracturing process thereof 德仕(成都)石油科技有限公司 2024-11-22 CN disclosed
CN-118878946-A Tire tread rubber for new energy heavy truck, and preparation method and application thereof 山东华盛橡胶有限公司 2024-11-01 CN disclosed
CN-118852750-A High-wear-resistance low-noise tire tread rubber for electric buses and preparation method and application thereof 山东华盛橡胶有限公司 2024-10-29 CN disclosed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP disclosed
US-20230175195-A1 PLASMA COATING TREATMENT METHOD FOR INHIBITING BIOLOGICAL PATHOGEN TRANSFER MOLECULAR PLASMA GROUP S.A. (LU) 2023-06-08 US disclosed
US-20230175195-A1 PLASMA COATING TREATMENT METHOD FOR INHIBITING BIOLOGICAL PATHOGEN TRANSFER MOLECULAR PLASMA GROUP S.A. (LU) 2023-06-08 US disclosed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO disclosed
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-10-02 US disclosed
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-10-02 US disclosed
US-7427394-B2 Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-23 US disclosed
US-7427394-B2 Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-23 US disclosed
WO-2008109105-A2 METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH SIRNA FLAGSHIP VENTURES (US) 2008-09-12 WO disclosed
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-06-19 US disclosed
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-06-19 US disclosed
EP-1903068-A1 Biodegradable poly(beta-amino esters) and uses thereof Massachusetts Institute of Technology (MIT) (US) 2008-03-26 EP disclosed
WO-2008011561-A2 END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-01-24 WO disclosed
WO-2007143659-A2 CROSSLINKED, DEGRADABLE POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability ACP1, ILK, BCAT2 TSHR 4541/4885ALDH1A1 891/4885TP53 1411/4885
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof PARN, PARG, POLL TSHR 4517/4885ALDH1A1 2664/4885TP53 2057/4885
US-20230175195-A1 PLASMA COATING TREATMENT METHOD FOR INHIBITING BIOLOGICAL PATHOGEN TRANSFER TFPI, TTPA, CD4 TSHR 3176/4885ALDH1A1 4478/4885TP53 3444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.