Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957693 | 0.88 | TLR8 (0.33) | TLR8ALOX5APFEN1IRAK4KCNQ3 | |
| SCHEMBL9893864 | 0.88 | TLR8 (0.33) | TLR8ALOX5APFEN1IRAK4KCNQ3 | |
| SCHEMBL11916150 | 0.74 | KCNQ3 (0.34) | TLR8ALOX5APFEN1IRAK4KCNQ3 | |
| SCHEMBL9945960 | 0.73 | ALDH1A1 (0.42) | — | |
| SCHEMBL9945966 | 0.71 | IRAK4 (0.46) | TLR8IRAK4 | |
| SCHEMBL29956725 | 0.69 | ENPP2 (0.39) | IRAK4 | |
| SCHEMBL2462591 | 0.69 | ENPP2 (0.39) | IRAK4 | |
| SCHEMBL14453810 | 0.68 | TLR8 (0.36) | TLR8ALOX5APFEN1IRAK4KCNQ3 | |
| SCHEMBL20149145 | 0.68 | TLR8 (0.36) | TLR8ALOX5APFEN1IRAK4 | |
| SCHEMBL264985 | 0.68 | ACLY (0.39) | IRAK4KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | TLR8 2162/4885ALOX5AP 1550/4885FEN1 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.