Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587748 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL8416 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL29636290 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL20659060 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL9945924 | 0.76 | NQO1 (0.43) | ALDH1A1KMT2AKAT6AFFAR4 | |
| SCHEMBL1020456 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL30829775 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10KAT6APOLB | |
| SCHEMBL29955317 | 0.75 | ALOX15 (0.40) | ALDH1A1KMT2APOLB | |
| SCHEMBL9945941 | 0.73 | TLR8 (0.31) | — | |
| SCHEMBL16379259 | 0.73 | TRPA1 (0.38) | ALDH1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885KMT2A 4328/4885PARP10 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.