Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893601 | 0.86 | CA2 (0.33) | PLAUCXCR5 | |
| SCHEMBL12517837 | 0.73 | FFAR4 (0.41) | PLAU | |
| SCHEMBL19940003 | 0.72 | PLAU (0.42) | PLAU | |
| SCHEMBL18726947 | 0.70 | CXCR5 (0.32) | PLAUCXCR5 | |
| SCHEMBL13639172 | 0.70 | SCN4A (0.48) | PLAUCXCR5 | |
| SCHEMBL12180582 | 0.70 | LMNA (0.37) | PLAU | |
| SCHEMBL2544650 | 0.70 | LMNA (0.36) | PLAU | |
| SCHEMBL104735 | 0.69 | SCN4A (0.48) | CXCR5 | |
| SCHEMBL12401803 | 0.68 | POLB (0.43) | PLAU | |
| SCHEMBL2542478 | 0.68 | KMT2A (0.50) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | PLAU 3260/4885CXCR5 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.