Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620707 | 1.00 | KMT2A (0.51) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13021341 | 0.81 | KMT2A (0.47) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL4922100 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13021342 | 0.80 | KMT2A (0.46) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL14620810 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13021347 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13021339 | 0.79 | DHODH (0.50) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13021378 | 0.79 | DHODH (0.50) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL802230 | 0.76 | KMT2A (0.73) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL4912911 | 0.76 | KMT2A (0.57) | KMT2AMEN1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899388-B1 | CATALYST SYSTEMS BASED ON AROMATIC DIIMINE LIGANDS | TOTAL PETROCHEMICALS RES FELUY (BE) | 2012-06-13 | — | — | EP | disclosed |
| US-7842829-B2 | Catalyst systems based on aromatic diimine ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-11-30 | — | — | US | disclosed |
| US-7842829-B2 | Catalyst systems based on aromatic diimine ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-11-30 | — | — | US | disclosed |
| US-20090131615-A1 | single site catalyst based on diimine ligands for oligomerizing or polymerizing ethylene and alpha-olefins; example is Bis-naphthyldi(9-fluorenylimine) complex with nickel dibromide | FINA TECHNOLOGY, INC. DAVID J. ALEXANDER (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090131615-A1 | single site catalyst based on diimine ligands for oligomerizing or polymerizing ethylene and alpha-olefins; example is Bis-naphthyldi(9-fluorenylimine) complex with nickel dibromide | FINA TECHNOLOGY, INC. DAVID J. ALEXANDER (US) | 2009-05-21 | — | — | US | disclosed |
| WO-2007006737-A1 | CATALYST SYSTEMS BASED ON AROMATIC DIAMINE LIGANDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-01-18 | — | — | WO | disclosed |
| EP-1741728-A1 | Catalyst systems based on aromatic diimine ligands. | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131615-A1 | single site catalyst based on diimine ligands for oligomerizing or polymerizing ethylene and alpha-olefins; example is Bis-naphthyldi(9-fluorenylimine) complex with nickel dibromide | PCNA, DDT, AOC1 | KMT2A 3964/4885MEN1 1153/4885MAPT 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.