SCHEMBL802230

SCHEMBL802230

Oc1ccccc1/N=C/c1c2ccccc2cc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 12/20 0.73
▸ MEN1 O00255 10/20 0.73
▸ GAA P10253 7/20 0.73
▸ MAPT P10636 7/20 0.73
▸ L3MBTL1 Q9Y468 3/20 0.73
▸ KDM4E B2RXH2 3/20 0.73
▸ ALDH1A1 P00352 2/20 0.73
▸ ATM Q13315 1/20 0.73
▸ POLB P06746 6/20 0.55
▸ DHODH Q02127 1/20 0.48
▸ LMNA P02545 3/20 0.47
▸ HTT P42858 2/20 0.46
▸ BLM P54132 2/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ AMY1A P0DUB6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301126 0.85 KMT2A (1.00) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL2029031 0.85 KMT2A (1.00) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL29785654 0.85 KMT2A (1.00) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL2029030 0.85 KMT2A (1.00) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL4922100 0.84 KMT2A (0.51) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL16323254 0.83 KMT2A (0.97) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL14537132 0.79 POLB (0.57) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL11406189 0.77 MEN1 (0.66) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL11406191 0.77 MEN1 (0.66) KMT2AMEN1GAAMAPTL3MBTL1
SCHEMBL26423315 0.77 MAPT (0.69) KMT2AMEN1GAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723268-B2 Organic light-emitting element LG CHEM, LTD. 2023-08-08 — — US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 — — US disclosed
US-9796684-B2 Materials for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-10-24 — — US disclosed
US-9796684-B2 Materials for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-10-24 — — US disclosed
US-9640766-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-05-02 — — US disclosed
US-9537105-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-01-03 — — US disclosed
US-20160276596-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-9334260-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-05-10 — — US disclosed
US-9334260-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-05-10 — — US disclosed
US-9199972-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-12-01 — — US disclosed
US-8679647-B2 Organic electroluminescent device comprising triazine derivatives MERCK PATENT GMBH (DE) 2014-03-25 — — US disclosed
US-20130053558-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 — — US disclosed
US-20130032764-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2013-02-07 — — US disclosed
US-20120228552-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 — — US disclosed
US-20120223276-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-09-06 — — US disclosed
US-20120168735-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2012-07-05 — — US disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 — — US disclosed
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 — — US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 KMT2A 1753/4885MEN1 2866/4885GAA 1005/4885
US-20130032764-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES TYMS, TYMP, NUDT1 KMT2A 3280/4885MEN1 2534/4885GAA 2478/4885
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO2B1, SLCO1B3, SLCO4C1 KMT2A 3563/4885MEN1 3164/4885GAA 1596/4885
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, ICMT, NUDC KMT2A 3703/4885MEN1 1890/4885GAA 2046/4885
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES KCNJ2, IKZF2, TERT KMT2A 1476/4885MEN1 4210/4885GAA 2882/4885
US-20130053558-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES PIEZO1, EMC1, EPCAM KMT2A 3436/4885MEN1 271/4885GAA 2534/4885
US-20120228552-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES ILK, VIM, NES KMT2A 3492/4885MEN1 1006/4885GAA 3601/4885
US-20120223276-A1 MATERIALS FOR ELECTRONIC DEVICES ERCC1, XPOT, EMD KMT2A 2079/4885MEN1 411/4885GAA 3150/4885
US-20160276596-A1 ORGANIC LIGHT EMITTING DIODE CRY2, CRY1, NR2E3 KMT2A 1242/4885MEN1 3240/4885GAA 2068/4885
US-11723268-B2 Organic light-emitting element CRY2, NR2E3, CRY1 KMT2A 931/4885MEN1 1662/4885GAA 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback