Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 12/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9894488 | 0.92 | GABRA5 (0.43) | GABRA5EGLN1GRM1 | |
| SCHEMBL9947559 | 0.86 | MAP4K4 (0.39) | — | |
| SCHEMBL9895430 | 0.83 | GABRA5 (0.44) | GABRA5EGLN1 | |
| SCHEMBL9947560 | 0.83 | GABRA5 (0.40) | GABRA5EGLN1GAA | |
| SCHEMBL9894510 | 0.80 | RAB9A (0.42) | GABRA5 | |
| SCHEMBL9894907 | 0.80 | GABRA5 (0.44) | GABRA5GRM1PHGDH | |
| SCHEMBL27933840 | 0.78 | KDM4C (0.42) | GABRA5 | |
| SCHEMBL6468600 | 0.77 | GABRA5 (0.49) | GABRA5GRM1 | |
| SCHEMBL9895449 | 0.75 | GABRA5 (0.53) | GABRA5EGLN1 | |
| SCHEMBL9895133 | 0.74 | GABRA5 (0.43) | GABRA5EGLN1GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076590-A1 | NOVEL TRIAZOLE COMPOUNDS III | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-14 | — | — | WO | disclosed |