Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886377 | 0.76 | SMN1; SMN2 (0.51) | ROCK2 | |
| SCHEMBL1609860 | 0.76 | CD38 (0.47) | ROCK2ROCK1 | |
| SCHEMBL22394688 | 0.76 | HDAC4 (0.50) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL28037674 | 0.75 | MMP2 (0.52) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL22394702 | 0.73 | HDAC4 (0.53) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9701078 | 0.72 | HDAC4 (0.52) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL4116189 | 0.72 | HDAC4 (0.52) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL4711538 | 0.72 | HDAC4 (0.52) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL4760506 | 0.72 | HDAC4 (0.52) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL22394634 | 0.72 | L3MBTL1 (0.54) | MMP2MMP9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165349-A1 | Phenyl-Substituted Pyrazolopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165349-A1 | Phenyl-Substituted Pyrazolopyrimidines | P2RX4, P2RY4, P2RX5 | MMP2 4764/4885MMP9 4729/4885CA12 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.