SCHEMBL9949346

SCHEMBL9949346

COC(=O)CN(CC(=O)O)c1cc(OC)c(OC)c(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 2/20 0.41
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLA2G2A P14555 1/20 0.40
BLM P54132 1/20 0.40
HSD17B10 Q99714 2/20 0.40
HTR1A P08908 1/20 0.40
HPGD P15428 1/20 0.40
HTR2C P28335 1/20 0.40
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39
MCL1 Q07820 1/20 0.39
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13603842 0.78 KEAP1 (0.52) ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2
SCHEMBL13603838 0.78 PLA2G2A (0.42) ALDH1A1POLBMAPK1PLA2G2ABLM
SCHEMBL9829986 0.78 ALDH1A1 (0.52) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL3841166 0.76 TDP1 (0.44) MEN1KMT2AALDH1A1POLBMAPK1
SCHEMBL13611311 0.75 PLA2G2A (0.40) ALDH1A1POLBMAPK1PLA2G2ABLM
SCHEMBL6227104 0.74 CA12 (0.49) ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2
SCHEMBL13680117 0.73 KEAP1 (0.46) KMT2AALDH1A1KDM4EPOLBMAPK1
SCHEMBL13603850 0.73 ALDH1A1 (0.40) ALDH1A1POLBPLA2G2ABLMLMNA
SCHEMBL9949291 0.73 MAPT (0.47) MEN1KMT2AALDH1A1KDM4EMAPK1
SCHEMBL13603843 0.72 ALDH1A1 (0.42) MEN1KMT2AALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471655-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2016-08-17 EP disclosed
CN-102529310-B Original edition of lithographic printing plate and lithographic process FUJI FILM CORP. (JP) 2015-09-16 CN disclosed
CN-102653158-B Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP 2015-04-15 CN disclosed
US-8435720-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2013-05-07 US disclosed
US-20120219911-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2012-08-30 US disclosed
EP-2471655-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2012-07-04 EP disclosed
US-20120160118-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-7582410-B2 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-20080038663-A1 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed