Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL3397893 | 1.00 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| Alcohol SCHEMBL9949549 | 1.00 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| Alcohol SCHEMBL9949554 | 0.97 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| Alcohol SCHEMBL5556315 | 0.95 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| Alcohol SCHEMBL9950687 | 0.92 | — | — | |
| Methyl Alcohol SCHEMBL27923539 | 0.86 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| SCHEMBL17046101 | 0.86 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| Alcohol SCHEMBL9949940 | 0.86 | — | — | |
| SCHEMBL3035987 | 0.86 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E | |
| SCHEMBL3036481 | 0.86 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1HSD17B10EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106943848-B | Carbon dioxide capture system and method of operating a carbon dioxide capture system | 株式会社东芝 | 2021-04-13 | — | — | CN | disclosed |
| EP-2705894-B1 | Acid gas absorbent, acid gas removal method and acid gas removal device | TOSHIBA KK (JP) | 2018-05-23 | — | — | EP | disclosed |
| EP-2468385-B1 | Acid gas absorbent, acid gas removal method and acid gas removal device | TOSHIBA KK (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-9409119-B2 | Acid gas absorbent, acid gas removal method, and acid gas removal device | KABUSHIKI KAISHA TOSHIBA (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-2705894-A1 | Acid gas absorbent, acid gas removal method and acid gas removal device | Kabushiki Kaisha Toshiba (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-20120161071-A1 | ACID GAS ABSORBENT, ACID GAS REMOVAL METHOD, AND ACID GAS REMOVAL DEVICE | KABUSHIKI KAISHA TOSHIBA (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-2468385-A2 | Acid gas absorbent, acid gas removal method and acid gas removal device | Kabushiki Kaisha Toshiba (JP) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161071-A1 | ACID GAS ABSORBENT, ACID GAS REMOVAL METHOD, AND ACID GAS REMOVAL DEVICE | ALKBH1, ALKBH3, ALKBH2 | SIGMAR1 224/4885ALDH1A1 247/4885HSD17B10 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.