SCHEMBL9951059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26081057	0.82	HSD11B1 (0.58)	MAPTPOLBMEN1ALDH1A1KMT2A
	SCHEMBL1855141	0.80	HSD11B1 (0.60)	MAPTPOLBMEN1ALDH1A1KMT2A
	SCHEMBL12613371	0.77	SRD5A2 (0.52)	KMT2AHDAC4
	SCHEMBL19650840	0.77	HSD11B1 (0.60)	MAPTPOLBMEN1ALDH1A1KMT2A
	SCHEMBL27642540	0.76	SRD5A2 (0.55)	KDM2BHDAC4
	SCHEMBL10200042	0.74	TRPV3 (0.47)	MAPTMEN1KMT2ALMNATRPV1
	SCHEMBL4023293	0.73	HSD11B1 (0.63)	MAPTPOLBTDP1KDM2BHSD11B1
	SCHEMBL9951087	0.72	TRPV3 (0.45)	MAPTMEN1KMT2ATRPV1HDAC4
	SCHEMBL10199934	0.71	TRPV3 (0.44)	MAPTMEN1KMT2ALMNATRPV1
	SCHEMBL2273492	0.71	LMNA (0.53)	MAPTKDM4ELMNAHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.