Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141039 | 0.95 | ALDH1A1 (0.49) | FKBP1ACTSSCTSLCTSBALDH1A1 | |
| SCHEMBL13733943 | 0.90 | EPHX2 (0.50) | FKBP1ACTSSCTSLCTSBALDH1A1 | |
| SCHEMBL12054389 | 0.87 | ALDH1A1 (0.51) | FKBP1ACTSSCTSLCTSBALDH1A1 | |
| SCHEMBL16665110 | 0.79 | EPHX2 (0.53) | FKBP1AALDH1A1GAAEPHX2EPHX1 | |
| SCHEMBL17141146 | 0.79 | CTSL (0.51) | CTSSCTSLCTSBALDH1A1GAA | |
| SCHEMBL26097271 | 0.77 | CTSS (0.47) | CTSSCTSLCTSBALDH1A1GAA | |
| SCHEMBL11119678 | 0.76 | FAAH (0.63) | ALDH1A1EPHX2TSHREPHX1FAAH | |
| SCHEMBL21027497 | 0.75 | EPHX1 (0.50) | CTSSCTSLCTSBALDH1A1GAA | |
| SCHEMBL1497415 | 0.75 | EPHX2 (0.54) | FKBP1AALDH1A1EPHX2EPHX1FAAH | |
| SCHEMBL21310438 | 0.75 | EPHX2 (0.49) | FKBP1AALDH1A1EPHX2FAAHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654422-A1 | BICYCLO[3.2.1]OCTYL AMIDE DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088365-A1 | BICYCLO[3.2.1]OCTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2012-06-28 | — | — | WO | disclosed |