SCHEMBL9952009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17680288	0.86	KIF11 (0.46)	KIF11CYP11B2EGLN2CYP11B1
	SCHEMBL24617109	0.85	KIF11 (0.62)	KIF11CYP11B2EGLN2CYP11B1
	SCHEMBL7634772	0.84	ALDH1A1 (0.48)	KIF11CYP11B2EGLN2ALDH1A1CYP11B1
	SCHEMBL27806613	0.83	KIF11 (0.47)	KIF11CYP11B2EGLN2ALDH1A1CYP11B1
	SCHEMBL12496569	0.81	PTGS1 (0.49)	CYP11B2EGLN2CYP11B1
	SCHEMBL13445154	0.81	KIF11 (0.54)	KIF11PTGDR2XDHKDM1ASLC1A3
	SCHEMBL13445159	0.81	KIF11 (0.54)	KIF11PTGDR2XDHKDM1ASLC1A3
	SCHEMBL23625527	0.81	ALDH1A1 (0.56)	CYP11B2ARKDM1AEGLN2ALDH1A1
	SCHEMBL8304491	0.80	SCN5A (0.46)	CYP11B2KDM1ACYP11B1MAOB
	SCHEMBL9951605	0.80	KIF11 (0.56)	KIF11PTGDR2CYP11B2ARKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.