SCHEMBL23625527

SCHEMBL23625527

Cc1ccc(-c2ccc(C#N)cc2C)cc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CYP2A6 P11509 1/20 0.56
KDM1A O60341 6/20 0.44
EGLN2 Q96KS0 4/20 0.43
CYP11B2 P19099 4/20 0.43
CYP11B1 P15538 3/20 0.43
HRH2 P25021 1/20 0.43
HRH1 P35367 1/20 0.43
AR P10275 1/20 0.42
S1PR1 P21453 1/20 0.41
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7634772 0.92 ALDH1A1 (0.48) ALDH1A1CYP2A6EGLN2CYP11B2CYP11B1
SCHEMBL27806613 0.90 KIF11 (0.47) ALDH1A1CYP2A6EGLN2CYP11B2CYP11B1
SCHEMBL29306075 0.90 ALDH1A1 (0.53) ALDH1A1CYP2A6KDM1ACYP11B2AR
SCHEMBL29306055 0.89 ALDH1A1 (0.57) ALDH1A1CYP2A6KDM1ACYP11B2AR
SCHEMBL14850863 0.89 ALDH1A1 (0.56) ALDH1A1CYP2A6KDM1ACYP11B2CYP11B1
SCHEMBL2786090 0.85 MMP3 (0.57) KDM1AEGLN2CYP11B2CYP11B1HRH2
SCHEMBL17629909 0.85 MAOA (0.43) KDM1AEGLN2CYP11B2CYP11B1HRH2
SCHEMBL12496569 0.85 PTGS1 (0.49) EGLN2CYP11B2CYP11B1HRH2HRH1
SCHEMBL2572264 0.85 ESR2 (0.53) ALDH1A1EGLN2CYP11B2CYP11B1AR
SCHEMBL29306094 0.84 ALDH1A1 (0.50) ALDH1A1CYP2A6KDM1ACYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed