SCHEMBL995234

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18411356	0.94	TSHR (0.50)	MMP3PTGS1TSHRCYP11B2ALDH1A1
	SCHEMBL11557444	0.86	HRH4 (0.44)	MMP3PTGS1TSHRCYP11B2KIF11
	SCHEMBL26274413	0.84	ABCG2 (0.50)	TSHRALDH1A1HRH4
	SCHEMBL31463164	0.83	TSHR (0.57)	MMP3PTGS1TSHRCYP11B2KIF11
	SCHEMBL26592149	0.83	ABCG2 (0.49)	CYP11B2
	SCHEMBL11618139	0.83	TSHR (0.52)	MMP3TSHRCYP11B2KIF11ALDH1A1
	SCHEMBL12681320	0.82	LOXL2 (0.46)	MMP3PTGS1TSHRCYP11B2KIF11
	SCHEMBL28056373	0.82	ALDH1A1 (0.43)	TSHRALDH1A1LAP3MAOBAR
	SCHEMBL26274420	0.82	EGLN2 (0.43)	CYP11B2ALDH1A1CYP2A6HRH4AR
	SCHEMBL13192345	0.81	IDO1 (0.39)	MMP3TSHRCYP11B2KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.