Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094562 | 0.84 | OXTR (0.72) | OXTRAVPR1ARAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL18498804 | 0.76 | OXTR (0.73) | OXTRAVPR1ARAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL9953226 | 0.75 | KEAP1 (0.54) | KEAP1NFE2L2SLC40A1GLO1BRD4 | |
| SCHEMBL30338836 | 0.72 | NAPRT (0.57) | KEAP1NFE2L2SLC40A1GLO1KMT2A | |
| SCHEMBL2371844 | 0.72 | NAPRT (0.57) | KEAP1NFE2L2SLC40A1GLO1KMT2A | |
| SCHEMBL15243732 | 0.72 | OXTR (0.63) | OXTRAVPR1ARAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL2227366 | 0.72 | NAPRT (0.57) | KEAP1NFE2L2SLC40A1GLO1KMT2A | |
| SCHEMBL784141 | 0.71 | KEAP1 (0.66) | KEAP1NFE2L2SLC40A1GLO1KMT2A | |
| SCHEMBL2565637 | 0.71 | KEAP1 (0.64) | KEAP1NFE2L2SLC40A1GLO1KMT2A | |
| SCHEMBL5015931 | 0.71 | KEAP1 (0.68) | KEAP1NFE2L2SLC40A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |