Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289136 | 0.85 | CACNA2D1 (0.51) | MEN1KMT2AATMCACNA2D1OPRM1 | |
| SCHEMBL31241091 | 0.82 | CACNA2D1 (0.47) | MEN1KMT2AALDH1A1ATMCACNA2D1 | |
| SCHEMBL9954332 | 0.82 | PTGS2 (0.45) | DPP4MEN1KMT2AATMCACNA2D1 | |
| SCHEMBL989394 | 0.80 | DYRK3 (0.46) | KMT2A | |
| SCHEMBL9953325 | 0.79 | HSD17B10 (0.49) | MEN1KMT2AALDH1A1ATMTSHR | |
| SCHEMBL9953300 | 0.77 | PDE5A (0.46) | DPP4MEN1KMT2AALDH1A1ATM | |
| SCHEMBL31241110 | 0.77 | PDE5A (0.46) | DPP4MEN1KMT2AALDH1A1ATM | |
| SCHEMBL9954631 | 0.76 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL9953607 | 0.75 | KMT2A (0.58) | MEN1KMT2AALDH1A1HSD17B10TDP1 | |
| SCHEMBL9954292 | 0.74 | PTGS2 (0.49) | MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |