Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955183 | 0.84 | CA12 (0.42) | ALDH1A1MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL9954126 | 0.81 | MAPT (0.43) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL9954421 | 0.79 | MEN1 (0.51) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL9670140 | 0.79 | MEN1 (0.51) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL9953980 | 0.79 | ATM (0.51) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL3337074 | 0.78 | PDE7A (0.63) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL17643003 | 0.78 | MEN1 (0.68) | ATMMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9953825 | 0.78 | MAPT (0.48) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL23958174 | 0.77 | MAPT (0.44) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL9952990 | 0.76 | KDM4E (0.52) | MEN1KMT2AALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |