Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954038 | 0.75 | GABRA1 (0.43) | ALDH1A1TDP1P2RX7SCDLOXL2 | |
| SCHEMBL9952337 | 0.74 | TAAR1 (0.44) | NR1H2NR1H3SLC40A1SLC22A12NFE2L2 | |
| SCHEMBL9953189 | 0.74 | NR1H2 (0.41) | NR1H2NR1H3P2RX7SLC40A1SLC22A12 | |
| SCHEMBL10873651 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TDP1P2RX7SCDLOXL2 | |
| SCHEMBL10292998 | 0.70 | KMT2A (0.53) | ALDH1A1SLC22A12 | |
| SCHEMBL5693095 | 0.70 | TDP1 (0.35) | ALDH1A1TDP1LOXL2PDPK1 | |
| SCHEMBL23644501 | 0.69 | GAA (0.35) | — | |
| SCHEMBL9953091 | 0.69 | NFE2L2 (0.36) | NR1H2NR1H3P2RX7SLC22A12NFE2L2 | |
| SCHEMBL3058083 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TDP1P2RX7SCDPDPK1 | |
| SCHEMBL5950061 | 0.66 | ADORA2A (0.40) | ALDH1A1LOXL2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |