Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952055 | 0.79 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL9953189 | 0.69 | NR1H2 (0.41) | NFE2L2NR1H2NR1H3SLC22A12P2RX7 | |
| SCHEMBL9952337 | 0.69 | TAAR1 (0.44) | NFE2L2NR1H2NR1H3SLC22A12 | |
| SCHEMBL9953159 | 0.69 | ALDH1A1 (0.40) | NFE2L2NR1H2NR1H3SLC22A12P2RX7 | |
| SCHEMBL9952641 | 0.69 | SLC40A1 (0.38) | HTR6 | |
| SCHEMBL9952851 | 0.69 | TP53 (0.33) | P2RX7 | |
| SCHEMBL9952650 | 0.67 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL9953076 | 0.66 | KDM4E (0.33) | DDR1 | |
| SCHEMBL10292998 | 0.66 | KMT2A (0.53) | SLC22A12 | |
| SCHEMBL9952655 | 0.64 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |