Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952807 | 0.82 | HTR2C (0.34) | HTR2CRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL9952864 | 0.79 | HTR2C (0.37) | HTR2CRAB9ANPC1THRBPOLB | |
| SCHEMBL9952318 | 0.79 | ALDH1A1 (0.35) | HTR2CRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL9951932 | 0.78 | ALDH1A1 (0.38) | HTR2CRAB9ANPC1THRBPOLB | |
| SCHEMBL9952001 | 0.78 | HTR2C (0.36) | HTR2CRAB9ANPC1THRBPOLB | |
| SCHEMBL9953820 | 0.78 | HTR2C (0.36) | HTR2CRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL9952034 | 0.74 | BRD4 (0.47) | HTR2CNPC1THRBALDH1A1KDM4E | |
| SCHEMBL9952936 | 0.73 | NPC1 (0.35) | HTR2CRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL9952060 | 0.73 | ALDH1A1 (0.40) | HTR2CPOLBALDH1A1KDM4EMAPT | |
| SCHEMBL29755406 | 0.70 | NPC1 (0.41) | HTR2CRAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |