Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953787 | 0.83 | PTPN1 (0.40) | NPC1RAB9AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL9952788 | 0.81 | HSD11B1 (0.33) | NPC1RAB9AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL9953917 | 0.80 | CBLB (0.36) | NPC1RAB9AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL9952318 | 0.79 | ALDH1A1 (0.35) | NPC1RAB9AKDM4EALDH1A1HTR2C | |
| SCHEMBL9952650 | 0.78 | P2RX7 (0.36) | NPC1RAB9AKDM4EALDH1A1HTR2C | |
| SCHEMBL9952807 | 0.75 | HTR2C (0.34) | NPC1RAB9AKDM4EALDH1A1HTR2C | |
| SCHEMBL9953831 | 0.74 | OPRK1 (0.34) | NPC1RAB9AHSD11B1OPRK1HTR2C | |
| SCHEMBL9953333 | 0.73 | HTR2C (0.33) | NPC1RAB9AKDM4EALDH1A1HTR2C | |
| SCHEMBL9952055 | 0.73 | P2RX7 (0.34) | ARTP53 | |
| SCHEMBL9952851 | 0.72 | TP53 (0.33) | ARTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |