Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953736 | 1.00 | GAA (0.41) | GAAPLAURECQLHTTKMT2A | |
| SCHEMBL8125788 | 0.80 | NNMT (0.46) | GAACNR2MAPTNNMTOPRK1 | |
| SCHEMBL9953358 | 0.80 | ALDH1A1 (0.38) | PLAUHTTKMT2ACNR2MAPT | |
| SCHEMBL16758468 | 0.76 | HTT (0.48) | GAAPLAUHTTKMT2AMAPT | |
| SCHEMBL16758469 | 0.76 | HTT (0.48) | GAAPLAUHTTKMT2AMAPT | |
| Lithium Ion SCHEMBL9954420 | 0.75 | CNR2 (0.37) | CNR2OPRK1 | |
| SCHEMBL14764185 | 0.75 | HTT (0.44) | HTTCNR2OPRK1 | |
| SCHEMBL316314 | 0.75 | HSD17B10 (0.50) | CNR2OPRK1 | |
| SCHEMBL14764171 | 0.73 | CNR2 (0.35) | GAACNR2NPSR1MAPTOPRK1 | |
| Lithium SCHEMBL9954426 | 0.73 | HSD17B10 (0.49) | CNR2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |