Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953825 | 0.88 | MAPT (0.48) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9955390 | 0.84 | MAPT (0.44) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9953451 | 0.83 | MAPT (0.44) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9953974 | 0.83 | KLKB1 (0.45) | KLKB1KLK1MAPTTHRBLMNA | |
| SCHEMBL9954127 | 0.79 | MAPT (0.46) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9953328 | 0.79 | MAPT (0.46) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9953332 | 0.79 | MAPT (0.46) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9953937 | 0.77 | MEN1 (0.46) | MAPTLMNATP53MEN1TSHR | |
| SCHEMBL9953860 | 0.77 | CYP1A2 (0.42) | MAPTTHRBLMNATP53MEN1 | |
| SCHEMBL9952990 | 0.76 | KDM4E (0.52) | MAPTTHRBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |