Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953825 | 0.91 | MAPT (0.48) | ALDH1A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL9955390 | 0.89 | MAPT (0.44) | ALDH1A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL9953751 | 0.83 | KLKB1 (0.45) | KLKB1KLK1F2LMNAMAPT | |
| SCHEMBL9953860 | 0.82 | CYP1A2 (0.42) | ALDH1A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL9953937 | 0.80 | MEN1 (0.46) | ALDH1A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL9953451 | 0.80 | MAPT (0.44) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9952990 | 0.79 | KDM4E (0.52) | ALDH1A1L3MBTL1LMNAHTTMAPT | |
| SCHEMBL9953908 | 0.79 | TP53 (0.47) | ALDH1A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL9954899 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9953328 | 0.76 | MAPT (0.46) | L3MBTL1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |