Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951996 | 0.77 | MEP1B (0.36) | SLC2A1MEP1B | |
| SCHEMBL9952809 | 0.77 | TAAR1 (0.45) | — | |
| SCHEMBL9952136 | 0.75 | MEP1B (0.39) | SLC2A1MEP1B | |
| SCHEMBL18263323 | 0.70 | DDR1 (0.37) | — | |
| SCHEMBL9929288 | 0.69 | ACLY (0.33) | ACLY | |
| SCHEMBL23673374 | 0.69 | AKR1B1 (0.40) | — | |
| SCHEMBL27176755 | 0.68 | KDM4E (0.43) | — | |
| SCHEMBL20303484 | 0.67 | PSEN1 (0.39) | — | |
| SCHEMBL20303695 | 0.67 | CA1 (0.34) | — | |
| SCHEMBL15137118 | 0.66 | BMP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |