Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951982 | 0.88 | NPC1 (0.32) | LRRK2NPC1RAB9AOPRK1ALDH1A1 | |
| SCHEMBL9952738 | 0.86 | RAB9A (0.33) | KMT2AMEN1ALOX12NPC1RAB9A | |
| SCHEMBL9953904 | 0.79 | HSD11B1 (0.39) | LRRK2TRPM5IL1BOPRK1HSD11B1 | |
| SCHEMBL9953108 | 0.77 | KMT2A (0.36) | KMT2ACCR2LRRK2MEN1ALOX15 | |
| SCHEMBL21895290 | 0.74 | KMT2A (0.39) | KMT2ALMNANPC1RAB9ATP53 | |
| SCHEMBL30772990 | 0.74 | KMT2A (0.39) | KMT2ALMNANPC1RAB9ATP53 | |
| SCHEMBL9952318 | 0.72 | ALDH1A1 (0.35) | KMT2ALMNAMEN1ALOX15ALOX12 | |
| SCHEMBL9952936 | 0.72 | NPC1 (0.35) | NPC1RAB9ATP53OPRK1HSD11B1 | |
| SCHEMBL29755406 | 0.71 | NPC1 (0.41) | KMT2AMEN1NPC1RAB9AHSD11B1 | |
| SCHEMBL3721717 | 0.71 | NPC1 (0.37) | LRRK2NPC1RAB9AOPRK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |