Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 11/20 | 1.00 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2259762 | 0.74 | CES1 (0.59) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL29711265 | 0.74 | CES1 (0.59) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL28965025 | 0.74 | CES1 (0.58) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL31492057 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL18930798 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL17818354 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL4092382 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL3845335 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL1749687 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 | |
| SCHEMBL31634050 | 0.73 | CES1 (0.57) | CES1TTRBCHETGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012099451-A1 | CURCUMIN COMPOUNDS CONTAINING INDOLIZINE AND THEIR PREPARATIONS THEREOF | UNIVERSITI SAINS MALAYSIA (MY) | 2012-07-26 | — | — | WO | claimed |
| WO-2012099452-A1 | CURCUMIN COMPOUNDS WITH SUPERIOR STRUCTURAL STABILITY AND PROCESSES FOR THEIR PREPARATION | UNIVERSITI SAINS MALAYSIA (MY) | 2012-07-26 | — | — | WO | claimed |
| WO-2012099454-A1 | CURCUMIN COMPOUNDS AND THEIR PREPARATIONS THEREOF | UNIVERSITI SAINS MALAYSIA (MY) | 2012-07-26 | — | — | WO | claimed |
| WO-2012099453-A1 | PYRROLOTHIAZOLE CONTAINING CURCUMIN COMPOUNDS | UNIVERSITI SAINS MALAYSIA (MY) | 2012-07-26 | — | — | WO | claimed |
| JP-61004726-A | — | — | None | — | — | JP | disclosed |
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |
| US-12110273-B2 | Method of preparing indolin-2-one compound and method of using indolin-2-one | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2024-10-08 | — | — | US | disclosed |
| US-20240043383-A1 | METHOD OF PREPARING INDOLIN-2-ONE COMPOUND AND METHOD OF USING INDOLIN-2-ONE | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2024-02-08 | — | — | US | disclosed |
| CN-115304536-A | Preparation and application of indoline-2-ketone compound derivative | 合肥工业大学 | 2022-11-08 | — | — | CN | disclosed |
| US-11192859-B2 | Quinoline compounds as modulators of RAGE activity and uses thereof | UNIV NEW YORK (US) | 2021-12-07 | — | — | US | disclosed |
| US-20190194136-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | UNIV NEW YORK (US) | 2019-06-27 | — | — | US | disclosed |
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| EP-1056435-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000038641-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038640-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038639-A1 | DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038638-A1 | DYEING METHOD USING A SPECIFIC ACTIVE METHYLENE COMPOUND AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| EP-0371444-A2 | Aromatic polycarbonate resin composition for molding | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276500-A2 | 2-Oxindole intermediates | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| JP-S614726-A | POLYCARBONATE RESIN OPTICAL MOLDING | MITSUBISHI GAS CHEM CO INC | 1986-01-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12110273-B2 | Method of preparing indolin-2-one compound and method of using indolin-2-one | HTR7, TPH2, IDO2 | CES1 1048/4885TTR 1603/4885BCHE 707/4885 |
| US-20240043383-A1 | METHOD OF PREPARING INDOLIN-2-ONE COMPOUND AND METHOD OF USING INDOLIN-2-ONE | IDO2, TPH2, HTR7 | CES1 1319/4885TTR 1669/4885BCHE 652/4885 |
| US-20190194136-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | AGER, HMGB1, GPR119 | CES1 2566/4885TTR 2388/4885BCHE 3360/4885 |
| US-11192859-B2 | Quinoline compounds as modulators of RAGE activity and uses thereof | AGER, HMGB1, GPR119 | CES1 2566/4885TTR 2388/4885BCHE 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.