Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289024 | 0.88 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9953024 | 0.85 | CA12 (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9953980 | 0.84 | ATM (0.51) | MAPTMEN1KMT2AATMALDH1A1 | |
| SCHEMBL10288659 | 0.83 | POLB (0.53) | MAPTMEN1KMT2AATMLMNA | |
| SCHEMBL14247198 | 0.83 | KMT2A (0.51) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29175100 | 0.82 | ALDH1A1 (0.70) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9954470 | 0.82 | HCAR1 (0.46) | MAPTMEN1KMT2AATMALDH1A1 | |
| SCHEMBL9953670 | 0.79 | ALDH1A1 (0.44) | MAPTMEN1KMT2AATMALDH1A1 | |
| SCHEMBL9954094 | 0.78 | HCAR1 (0.51) | MAPTATMHCAR1 | |
| SCHEMBL9994903 | 0.78 | HCAR1 (0.47) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |