Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953980 | 0.89 | ATM (0.51) | HCAR1MAPTATMMEN1KMT2A | |
| SCHEMBL10288659 | 0.85 | POLB (0.53) | HCAR1MAPTATMMEN1KMT2A | |
| SCHEMBL9954589 | 0.84 | ALOX12 (0.50) | MAPTATMMEN1KMT2AALDH1A1 | |
| SCHEMBL9954343 | 0.82 | MAPT (0.49) | HCAR1MAPTATMMEN1KMT2A | |
| SCHEMBL9954094 | 0.80 | HCAR1 (0.51) | HCAR1MAPTATMPTGS2PI4KA | |
| SCHEMBL9954631 | 0.77 | KMT2A (0.46) | MAPTATMMEN1KMT2AALDH1A1 | |
| SCHEMBL9954958 | 0.77 | ALDH1A1 (0.47) | MAPTATMMEN1KMT2AALDH1A1 | |
| SCHEMBL10289024 | 0.77 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9955586 | 0.74 | HPD (0.44) | HCAR1MEN1KMT2ASMN1; SMN2PI4KA | |
| SCHEMBL9955387 | 0.74 | TDO2 (0.50) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |