Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170360 | 0.88 | CA12 (0.42) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL5258570 | 0.78 | CYP1A2 (0.46) | DAOCYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL5540730 | 0.77 | SOD1 (0.47) | DAO | |
| SCHEMBL514661 | 0.77 | APP (0.42) | MAOBAPPCA12CA1CA2 | |
| SCHEMBL3251102 | 0.77 | SYK (0.46) | DAOMAOBAPPCYP1A2CYP2D6 | |
| SCHEMBL3830326 | 0.77 | CA12 (0.53) | MAOBAPPCA12CA1CA2 | |
| SCHEMBL6978990 | 0.77 | TDP1 (0.52) | MAOBAPPCA12CA1CA2 | |
| SCHEMBL514644 | 0.77 | L3MBTL1 (0.47) | MAOBPARP10L3MBTL1NPC1 | |
| SCHEMBL2641227 | 0.77 | LTA4H (0.47) | APPCYP1A2CYP2C19 | |
| SCHEMBL28675145 | 0.77 | CYP1A2 (0.44) | DAOMAOBAPPCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777640-B | Pyrazole cyclohexanediol ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-105777640-A | Pyrazole cyclohexanediol ether compounds and applications thereof | 沈阳中化农药化工研发有限公司 | 2016-07-20 | — | — | CN | claimed |
| US-6107284-A | Water-soluble derivatives of epipodophyllotoxin, process for their preparation, their use as medicinal products and their intended use in anti-cancer treatments | PIERRE FABRE MEDICAMENT (FR) | 2000-08-22 | — | — | US | claimed |
| EP-0787135-B1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PF MEDICAMENT (FR) | 2000-05-24 | — | — | EP | claimed |
| EP-0787135-A1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1997-08-06 | — | — | EP | claimed |
| EP-0675895-B1 | ETOPOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A DRUG AND IN THE PREPARATION OF A DRUG FOR TREATING CANCER | PF MEDICAMENT (FR) | 1997-07-23 | — | — | EP | claimed |
| US-5643885-A | Etoposide derivatives, process for preparing them, their use as a medicinal product and their use for the preparation of a medicinal product intended for anti-cancer treatment | PIERRE FABRE MEDICAMENT (FR) | 1997-07-01 | — | — | US | claimed |
| JP-H08504795-A | — | — | 1996-05-21 | — | — | JP | claimed |
| WO-1996012727-A1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |
| EP-0675895-A1 | ETOPOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A DRUG AND IN THE PREPARATION OF A DRUG FOR TREATING CANCER. | FABRE PIERRE COSMETIQUE (FR) | 1995-10-11 | — | — | EP | claimed |
| EP-0469888-B1 | Amidobenzenes | ICI PLC (GB) | 1994-09-28 | — | — | EP | claimed |
| WO-1994014829-A1 | ETOPOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A DRUG AND IN THE PREPARATION OF A DRUG FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1994-07-07 | — | — | WO | claimed |
| US-5250570-A | Aldose reductase inhibitors for controlling side effects of diabetes and galactosemia | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-05 | — | — | US | claimed |
| EP-0469888-A1 | Amidobenzenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-2024129931-A1 | ALPHA-V BETA-6(ανβ6) INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-105777640-B | Pyrazole cyclohexanediol ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-01-07 | — | — | CN | disclosed |
| EP-2257297-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF ACNE, SEBORRHOEA AND SEBHORROEIC DERMATITIS, OR FOR REDUCING SEBUM SECRETION | MIMETICA PTY LTD (AU) | 2017-10-18 | — | — | EP | disclosed |
| US-4458071-A | Process for 1-oxa-β-lactams | ELI LILLY AND COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0109302-A1 | Process for 1-oxa-beta-lactams | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4042472-A | Electrolytic process for 7-methoxy-3-exomethylenecepham compounds | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |