Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959889 | 0.83 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL9953694 | 0.81 | ALPL (0.34) | DGAT1 | |
| SCHEMBL3508463 | 0.76 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL9952816 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL9954569 | 0.74 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL9953536 | 0.73 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL21259853 | 0.72 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL27193468 | 0.71 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL23294447 | 0.70 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL29851912 | 0.70 | DGAT1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |