Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954498 | 0.83 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9952972 | 0.81 | ALPL (0.33) | DGAT1 | |
| SCHEMBL9954569 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL9952816 | 0.76 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL9954260 | 0.74 | RAB9A (0.38) | MAPTNPC1RAB9A | |
| SCHEMBL20299197 | 0.73 | LMNA (0.40) | DGAT1MAPTLMNARECQLHDAC6 | |
| SCHEMBL9953536 | 0.72 | DGAT1 (0.32) | DGAT1NPC1 | |
| SCHEMBL27193468 | 0.70 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL31419057 | 0.69 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL31418204 | 0.69 | MAPT (0.39) | MAPTLMNATP53RECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |