Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282031 | 0.89 | HDAC8 (0.56) | HDAC8HTR1AHTR7DRD2RORC | |
| SCHEMBL783637 | 0.86 | SMN1; SMN2 (0.56) | HDAC8HTR1AHTR7DRD2RORC | |
| SCHEMBL15225912 | 0.85 | SMN1; SMN2 (0.59) | HDAC8HTR1AHTR7ALDH1A1KDM4E | |
| SCHEMBL18343804 | 0.81 | KDM4E (0.56) | HTR1AHTR7ALDH1A1KDM4ERECQL | |
| Bicarbonate SCHEMBL15226047 | 0.80 | NAMPT (0.57) | HDAC8HTR1AHTR7ALDH1A1KDM4E | |
| SCHEMBL30585992 | 0.79 | IKBKB (0.48) | HDAC8HTR1AHTR7DRD2RORC | |
| SCHEMBL29086059 | 0.79 | IKBKB (0.48) | HDAC8HTR1AHTR7DRD2RORC | |
| Hydrochloric Acid SCHEMBL21640226 | 0.78 | IKBKB (0.47) | HDAC8HTR1AHTR7DRD2RORC | |
| SCHEMBL21959842 | 0.77 | ALDH1A1 (0.59) | HDAC8ALDH1A1SMN1; SMN2NAPRT | |
| SCHEMBL28802164 | 0.77 | HTR1A (0.54) | HDAC8HTR1AHTR7DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |