Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952694 | 0.83 | NPSR1 (0.46) | ALDH1A1CCR4SHMT2NPC1POLB | |
| SCHEMBL14305924 | 0.81 | SHMT2 (0.40) | ALDH1A1CCR4SHMT2PIK3CANPC1 | |
| SCHEMBL14305925 | 0.80 | SHMT2 (0.39) | NR3C1ALDH1A1CCR4SHMT2NPC1 | |
| SCHEMBL9954777 | 0.80 | PIK3CD (0.56) | CCR4SHMT2PIK3CANPC1PIK3CD | |
| SCHEMBL9954663 | 0.78 | ALPL (0.60) | CNR1NR3C1ALOX5APFEN1CNR2 | |
| SCHEMBL9958880 | 0.77 | SHMT2 (0.39) | ALDH1A1CCR4SHMT2PIK3CANPC1 | |
| SCHEMBL9953570 | 0.77 | LMNA (0.55) | ALDH1A1MAPK1POLB | |
| SCHEMBL9953641 | 0.76 | SHMT2 (0.44) | ALDH1A1CCR4SHMT2NPC1PIK3CD | |
| SCHEMBL21512607 | 0.75 | KDM4E (0.53) | ALDH1A1CCR4SHMT2PIK3CG | |
| SCHEMBL30866828 | 0.75 | KDM4E (0.53) | ALDH1A1CCR4SHMT2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |